increased/decreased transcription

[fypoadmin]

(sorry about this)

I just used this term, but should it really be a narrow synonym of 'mRNA accumulation'? Or child. C.f protein accumulation and not knowing if something is made in larger quantities / or is more stable.

Same for decreased transcription...

Original comment by: Antonialock

[fypoadmin]

I think it would depend on the experiment: if you just measure the amount of RNA, that doesn't tell you whether there's more because of more transcription or greater stability/less degradation. But if the experiment measures, say, hot NTP incorporation into RNA products, you can be more confident that you're detecting changes in transcription.

Original comment by: mah11

[fypoadmin]

these are for bog-standard northerns (all the examples I have)

Original comment by: Antonialock

[fypoadmin]

I've added these:

altered RNA level FYPO:0000824 increased RNA level FYPO:0000825 decreased RNA level FYPO:0000826

and put comments on them as well as the increased/decreased transcription terms

Original comment by: mah11

[fypoadmin]

• status: open --> open-fixed

Original comment by: mah11

[fypoadmin]

ok cool, I just updated my file with svn but can't see it yet, sounds good though

Original comment by: Antonialock

[fypoadmin]

oh, sorry, it's still just in my OBO-Edit; I'll commit it before I go home today

Original comment by: mah11

[fypoadmin]

could you also add normal mRNA level....(it exists for protein level)

Original comment by: Antonialock

[fypoadmin]

normal RNA level FYPO:0000840

will be committed later today

Original comment by: mah11

[fypoadmin]

closing - term is now in curation tool

Original comment by: mah11

[fypoadmin]

• status: open-fixed --> closed-fixed

Original comment by: mah11