pombase / fypo

Fission Yeast Phenotype Ontology
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dumbbell follow up #1185

Closed fypoadmin closed 9 years ago

fypoadmin commented 11 years ago

I still have a note that I need

"germinated spores swollen dumbbell shaped" (I think this phenotype is elongated, but also wide so it is classed as swollen)

I think this is describing the same genes that Antonia submitted a ticket about the other day is related to the ticket Antonia submitted the other day (I looked for it but I can't find it, possibly cdc8?). We should compare both phenotypes to make sure that they are the same. I'll put this in the "questions for jacky"

Original comment by: ValWood

fypoadmin commented 11 years ago

um, I think I'll hold off until you've talked to Jacky, 'cos I'm a little confused by this initial request ...

Original comment by: mah11

fypoadmin commented 10 years ago

germinated spores swollen dumbbell shaped

yep this is the phenotype. Jacky drew a small spore which doesn't elongate (it never looks like a vegetative cell, just looked like a small dumbbell). So, this is a different dumbbell to FYPO:0000779 FYPO:0001006

but it does apply to the same genes....

Original comment by: ValWood

fypoadmin commented 10 years ago

my notes say: essential misshapen spore, dumbbell shaped with swollen ends (normal length)

It never looks like a proper cell because the conjugation tube doesn't form

Original comment by: ValWood

fypoadmin commented 10 years ago

Wait to do this one to. There are some inconsistencies. I will report back

Original comment by: ValWood

fypoadmin commented 10 years ago

The term request is fine. I wanted to know why other cdc8 deletion was different but the other cdc8 was a disruption rather than a deletion

Original comment by: ValWood

fypoadmin commented 10 years ago

So, to follow the pattern of existing terms, should I add:

inviable after spore germination, without cell division, swollen dumbbell-shaped cell ?

Also, 'inviable elongated dumbbell-shaped cell' (FYPO:0000779) has the comment "Note that all dumbbell-shaped cells observed are also elongated. ...". Should that change?

Original comment by: mah11

fypoadmin commented 10 years ago

not sure, it seems so but shouldn't swollen, by definition be both "longer" and "wider"

Checking with Jacky again.

v

Original comment by: ValWood

fypoadmin commented 10 years ago

Generic "swollen" is defined as "larger volume than normal", without saying anything about longer vs wider vs both.

Original comment by: mah11

fypoadmin commented 10 years ago

Ah OK, I think of swollen as also being longer+wider. Thats not tru for a large rounded cell is is? But if a normal shape cell is both longer+wider that = swollen?

Original comment by: ValWood

fypoadmin commented 10 years ago

tbh, I haven't really thought properly about rounded/spheroid cells ...

certainly I'd call a cell swollen if it's longer+wider, but same length:width ratio as wt

I'm less sure that I wouldn't call a higher-volume rounded cell swollen too ... but I'm not a lifelong pombologist ;)

Original comment by: mah11

fypoadmin commented 10 years ago

we also have "swollen spheroid" terms (for [fission-yeast-phenotype:#800])

Original comment by: mah11

fypoadmin commented 10 years ago

OK, I've added this:

inviable after spore germination, without cell division, swollen dumbbell-shaped cell FYPO:0002987

and amended the comment on FYPO:0000779 so it says "usually" instead of "all dumbbells".

If that sorts everything, I'll close this.

Original comment by: mah11

fypoadmin commented 10 years ago

Original comment by: mah11

fypoadmin commented 10 years ago

I know you'll open a new ticket if you need anything else ;)

Original comment by: mah11