fypoadmin
commented
12 years ago have finally had a look at this ...
The challenge, I think, is that what happens in the presence of caffeine + (HU or IR) probably shouldn't be considered "normal" -- with caffeine, the cell doesn't show its normal response (i.e. stopping at checkpoint) to HU/IR. So I don't think there's going to be a nice handy GO term to point to in a phenotype term.
I could just add a term and not have an xp (or ask George if he has any ideas ... maybe could use more than one GO term?)
"DNA damage checkpoint override in response to caffeine abolished" or something to that effect?
Original comment by: mah11
I am tidying up the random qualifiers which I couln't move to annotation extensions
For this one /controlled_curation="term=phenotype, DNA damage checkpoint defects; qualifier=caffeine_mediated_override|required; db_xref=PMID:10224243; cv=phenotype; date=19700101"
This one looks as though there should be a "different" phenotype term to describe this http://www.ncbi.nlm.nih.gov/pubmed/10224243?dopt=Abstract
for now I am deleting this phenotype annotation and we can make a new one whenever (no hurry can wait until after migration)
Original comment by: ValWood