pombase / fypo

Fission Yeast Phenotype Ontology
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high temperature #2107

Closed fypoadmin closed 9 years ago

fypoadmin commented 9 years ago

I was just about to ask for "abolished growth on high temp" but I wonder if we could streamline some terms and merge "loss of viability at high temperature" and "decreased cell population growth at high temperature" with new merged term being called "sensitive to high temperature"?

Original comment by: Antonialock

fypoadmin commented 9 years ago

I only use the "loss of viability at high temperature" term when they do the type of experiment where they take aliquots of a culture at high temperature and see how many colonies form when they plate them back at std/low temperature. That isn’t a direct measure of population growth at high temp.

If there's just growth or lack thereof on a plate or in liquid (but most commonly a photo of a plate) at high temp, then I use "decreased population growth" or "inviable", and I don't use the "loss of viability" term. Lately I've been putting temp in as a condition rather than using the pre-composed term, but both way of doing it are semantically equivalent and therefore interchangeable in principle.

But I don't think there's a case for merging "loss of viability" and "decreased cell population growth" for high temp or any other condition, because they fit slightly different experiments. The "loss of viability" terms all have a brief explanation of the expt in comments; would it help if I moved that stuff to the defs?

Original comment by: mah11

fypoadmin commented 9 years ago

no it's ok!

Original comment by: Antonialock

fypoadmin commented 9 years ago

So do you want any new terms here?

Original comment by: mah11

fypoadmin commented 9 years ago

hmmmm.....not sure if we need the distinction abolished/decreased growth at hi temp?

Original comment by: Antonialock

fypoadmin commented 9 years ago

hmmm indeed. I've tended to use inviable+condition if there's no detectable growth at high temp ...

Original comment by: mah11

fypoadmin commented 9 years ago

hmm, I think I would prefer a new term to help searching

Not sure whether the high temp phenotypes are useful but many of the cs mutants seem to be cytoskeletal, better to capture the detail than to realize down the line that we should have

Original comment by: Antonialock

fypoadmin commented 9 years ago

Original comment by: mah11

fypoadmin commented 9 years ago

if you want to use it, no problem to add it:

abolished cell population growth at high temperature FYPO:0004481

Original comment by: mah11