pombase / fypo

Fission Yeast Phenotype Ontology
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actin cytoskeleton phenotypes #4112

Open ValWood opened 2 years ago

ValWood commented 2 years ago

I don't fully understand the difference between

abnormal actin cytoskeleton (FYPO:0005665) A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal.

AND abnormal actin cytoskeleton organization (FYPO:0004803) A cellular process phenotype in which actin cytoskeleton organization is abnormal.

(all of the annotations to abnormal actin cytoskeleton (FYPO:0005665) are also annotated to FYPO:0004803)

I'm not sure why amount/distribution/morphology are not 'organization'

Need to look at logical defs.

ValWood commented 2 years ago

similarly "abnormal cell wall' and 'abnormal cell wall organization'

I can see the difference, but for users it seems a bit arbitrary.

For example "cell wall invagination into cytoplasm (FYPO:0003697)" is under abnormal cell wall, but not under morphology, hence abnormal cell wall organization. But, it is clearly both?

ValWood commented 2 years ago

@manulera I think we are converging. There is a difference between these types of terms for an ontology purist, but is it helpful for users? We should take advice about this. The uPheno people may have experience here.