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Fission Yeast Phenotype Ontology
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Changes to decreased horsetail movement (FYPO:0004605) #4153

Closed manulera closed 2 years ago

manulera commented 2 years ago

Changes to decreased horsetail movement (FYPO:0004605)

The current definition of this term is:

A cellular process phenotype in which the occurrence of horsetail movement is decreased. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I.

Initially I thought this would be a similar case of yes/no phenotype (abolished horsetail with a certain penetrance). It's not the case, but I think some clarifications could be made.

The term makes sense for PMID:24954111, where they measured the total length travelled by the SPB during horsetail movement. This is an interesting phenotype because it can be that in a mutant that has abnormal horsetail nucleus due to detached telomeres, the SPB still travels the same distance. See Fig. B below.

Proposed change of the definition and term name

decreased distance travelled by the spindle pole body during horsetail movement

A cellular process phenotype in which the total distance travelled by the SPB during horsetail movement is decreased. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I.

Phenotypes I believe are wrongly annotated to this term

Next steps if you agree

manulera commented 2 years ago

Logical definition will have to be updated as a consequence #4173