Can MiXeR analysis be performed on any phenotype, or are there minimum N, Neff or SNP-h2 requirements?
After reading some papers, I understood it is suggested to have over 50,000 sample size (N > 50,000) and SNP-h2 above 0.05, but from my results, I see that a larger sample size may make up for lower SNP-h2 (and vice-versa), and I get both positive AIC and BIC values.
How should I determine the reliability of MiXeR analysis results? Should I rely solely on AIC and BIC values, or should other factors (mentioned above) be considered before reporting the results?
Hello,
Can MiXeR analysis be performed on any phenotype, or are there minimum N, Neff or SNP-h2 requirements?
After reading some papers, I understood it is suggested to have over 50,000 sample size (N > 50,000) and SNP-h2 above 0.05, but from my results, I see that a larger sample size may make up for lower SNP-h2 (and vice-versa), and I get both positive AIC and BIC values.
How should I determine the reliability of MiXeR analysis results? Should I rely solely on AIC and BIC values, or should other factors (mentioned above) be considered before reporting the results?