privefl / bigsnpr

R package for the analysis of massive SNP arrays.
https://privefl.github.io/bigsnpr/
183 stars 43 forks source link

Imputation for haploid organisms #485

Open adomron24 opened 3 months ago

adomron24 commented 3 months ago

Hello,

I would like to use bigsnpr to compare the output of clumping vs pruning in my snps dataset from Zymoseptoria tritici. As it is an haploid organism, and I have selected only bialellic snps, I only have 0 (reference) or 2 (alternate) values for my variants after converting the .bed file from plink to bigsnp object.

However, when I try to impute the missing values I end up having "1" values, which would be incorrect since no heterozygous variants should be found. Is there any additional parameter recommended to fix this?

Thank you,

Alex

privefl commented 3 months ago
privefl commented 2 months ago

Any update on this?