search

psathyrella / partis

B- and T-cell receptor sequence annotation, simulation, clonal family and germline inference, and affinity prediction
GNU General Public License v3.0
57 stars 34 forks source link

Figure out relationship between sequences that logprob and naive hfrac get right/wrong #171

Closed psathyrella closed 8 years ago

psathyrella commented 8 years ago

Perhaps a more useful way to describe it: how can we do a better job of identifying the sequences which naive hfrac gets wrong (so we can instead run the expensive lratio)?

matsen commented 8 years ago

Duncan:

We have these two metrics, and we use them both. Perhaps we can find characteristics of sequences for which we would want to use them differently.

Perhaps distance to germline?