qc17-THU / DL-SR

Tensorflow/keras implementation for image transformation from low-resolution (LR) image to super-resolved one, including single wide-field (WF) image super-resolution prediction and SIM reconstruction.
MIT License
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Clarification on the SIM Data #21

Open jim-j-james opened 1 year ago

jim-j-james commented 1 year ago

Following is the extract from the paper and i have marked the corresponding files names for CCP's. Seems #2 is not available in the data shared. Is my understanding correct?

1. For each ROI, we acquired nine sets of N-phase × M-orientation raw images with constant 1 ms exposure time but increasing the excitation light intensity, where N and M are three for TIRF-SIM and GI-SIM, and five for nonlinear SIM. - *RawSIMDatalevel.mrc**

2. Meanwhile, each set of N × M raw images was reconstructed into a SIM image attributing the same fluorescence level as the

corresponding WF image, which served as a reference to assess the quality of the DLSR image at that fluorescence level. - Missing

3 - In addition, in the same ROI, we finally elevated the excitation intensity and exposure time (typically 120 W cm−2 for 10 ms) to achieve a high fluorescence level of >1,200 average photon count, and independently acquired three sets of N × M raw images. The resulting three SIM images of ultrahigh SNR were averaged as the GT-SIM image to guarantee high quality. SIM_gt.mrc