raphael-group / GASTON

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Handling low-quality cells #6

Closed simonmfr closed 4 weeks ago

simonmfr commented 1 month ago

GASTON recognizes low-quality cells (with few reads) as a separate domain. Should these cells be excluded before running GASTON, or is it important to include them in the raw data analysis? Thanks!

uthsavc commented 1 month ago

I would suggest removing these cells. Leaving this open for now: I'll add some pre-processing code to the tutorial for removing cells with UMI count < some threshold.

simonmfr commented 1 month ago

Great, thanks.

uthsavc commented 4 weeks ago

I updated the Visium/Slide-Seq tutorials (colorectal tumor and cerebellum, respectively) to expose a minimum UMI threshold.