Tumor Heterogeneity Analysis (THetA) and THetA2 are algorithms that estimate the tumor purity and clonal/subclonal copy number aberrations directly from high-throughput DNA sequencing data. This repository includes the updated algorithm, called THetA2.
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2. chromosome number (Integer) - chromosome on which the interval
occurs
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This seems unnecessarily restrictive and creates extra work for the end user. Why not allow values like chr1 and chrM ? I've seen other bioinformatics Python packages with this unusual limitation, too.
Thank you for bringing this to our attention. The code already accepted chrmN format and we updated the code to accept chrN format. The manual has been updated the manual to describe allowed formats.
This seems unnecessarily restrictive and creates extra work for the end user. Why not allow values like chr1 and chrM ? I've seen other bioinformatics Python packages with this unusual limitation, too.