Tumor Heterogeneity Analysis (THetA) and THetA2 are algorithms that estimate the tumor purity and clonal/subclonal copy number aberrations directly from high-throughput DNA sequencing data. This repository includes the updated algorithm, called THetA2.
THetA can't run on OSX with multiple processes due to this issue: http://stackoverflow.com/questions/5900985/multiprocessing-queue-maxsize-limit-is-32767
This could be solved by either setting MAX_QUEUE_SIZE = 2**15-1 (or lower), or to -1 (effectively infinite)