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rcedgar / muscle

Multiple sequence and structure alignment with top benchmark scores scalable to thousands of sequences. Generates replicate alignments, enabling assessment of downstream analyses such as trees and predicted structures.
https://drive5.com/muscle
GNU General Public License v3.0
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double free or corruption (!prev)eriors #34

Closed Adarsh931 closed 1 year ago

Adarsh931 commented 2 years ago

I was using muscle5 for alignment of around 10k sequences, I am getting the following error:

muscle 5.1.linux64 [12f0e2]  528Gb RAM, 56 cores
Built Jan 13 2022 23:17:13
(C) Copyright 2004-2021 Robert C. Edgar.
https://drive5.com

Input: 9988 seqs, avg length 745, max 3209

WARNING: >1k sequences, may be slow or use excessive memory, consider using -super5

00:40 4.9Gb  CPU has 56 cores, running 36 threads
double free or corruption (!prev)eriors
rcedgar commented 2 years ago

Does this error reproduce every time you try? I would be glad to take a look if you post the input somewhere I can download it -- if so, please try binary search to reduce the number of input sequences as follows: divided the input in half, try each half, if one fails then repeat with the half.

Adarsh931 commented 2 years ago

Looks like there was some problem with my sequence itself. Issue is resolved now.