Closed bioinfonerd closed 1 year ago
This is because the sequences are MUCH too long for muscle (or any other MSA program I know of). Sequences this long have re-arrangement events and therefore do not have global alignments. The practical limit on sequence length in the current muscle is very roughly 20k letters.
Thank you for the response
Love working with muscle, but I have a current alignment issue. I want to compile a consensus sequence from 11 sequences that are ~2,500,000 in length. Computer resources are not an issue, but seems max memory allowed is 215Mb. Is there a way I can change this?