Open sbliven opened 8 years ago
I see some complications in combining short repeats into longer ones, because the final length of the repeats is only known after optimization. Thus, it would require an additional optimization after merging some of the repeats.
In addition, we would need to know the optimal factor of the number of repeats to combine. For example:
On the one hand I agree that the repeat number and length is very much dependent on the optimal self-alignment, and that is a problem for short OPEN repeats. The order detector has less information than for CLOSED repeats. On the other hand, this only applies to very short repeats (less than 15 residues), which have generally poor signal and are better detected by other algorithms (solenoid or TPR detection), so CE-Symm is not the optimal approach for detecting them.