TRBJ2-7*02 X02987 FR4Begin should be 19 instead of 20

repseqio / library-imgt

IMGT segment library converted to RepSeq.IO JSON format

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TRBJ2-7*02 X02987 FR4Begin should be 19 instead of 20 #13

Open yma-pact opened 2 years ago

yma-pact commented 2 years ago

By comparing FR4Begin of human TRBJ2-701 and TRBJ2-702, TRJBJ2-7*02 should be changed from 20 to 19. As a consequence, mixCR will produce a consensus VDJ sequence missing the bp "G" and wrong FR4 tranlation due to this error label.

bshim181 commented 5 months ago

These errors are still present and need to be addressed. I noticed several instances where CDR3 sequences are getting translated in wrong frame and lead to a missing clonotype