Exact Global P value MR-PRESSO

rondolab / MR-PRESSO

Performs the Mendelian Randomization Pleiotropy RESidual Sum and Outlier (MR-PRESSO) method.

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Exact Global P value MR-PRESSO #8

Open Cerinthe opened 5 years ago

Cerinthe commented 5 years ago

The result of the P value of the MR-PRESSO Global test I get is "<0.001". Is it possible to get the exact P value instead? Many thanks!

rondolab commented 5 years ago

Hi, Since the global P-value is an empirical P-value the only way to get the exact P-value is to increase the number of permutations by increasing "NbDistribution" to obtain the precision you want (~1/NbDistribution). Best.