ropensci / phylotaR

An automated pipeline for retrieving orthologous DNA sequences from GenBank in R
https://docs.ropensci.org/phylotaR
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Infrasturcture and support for blastn alternatives #33

Closed DomBennett closed 1 year ago

DomBennett commented 6 years ago

There are alternatives to NCBI's blastn that are often much faster, but:

There is a large number: https://en.wikipedia.org/wiki/List_of_sequence_alignment_software In particular: usearch, blat, megablast, plast, diammond (nucleotide capabilities pending: https://github.com/bbuchfink/diamond/issues/117)

Instead of developing a new code for each individual search tool alternative, provide the user with general input/output functions that a user could adapt for their own choice of search tool. The benefits of this solution:

DomBennett commented 6 years ago

With thanks to @mtop