hujo91
commented
2 years ago futhermore some more minor updates & improvements:
- correction of wrong RXNO IRI (see #12 )
- addition of has_exact_synonym "CBS reduction" to "Corey-Bakshi-Shibata reduction" (RXNO:0000597)
- import of some new substances from ChEBI under "molecular entity" class
- updated "date" annotion field of RXNO
Addition of 8 more reactions:
nitroxide exchange reaction (RXNO:0000663) Def.: Nitroxide exchange reactions are based on thermal C–O bond homolysis of alkoxyamines, which leads to transient carbon-centred radicals and persistent nitroxide radicals. Usually these carbon centred radicals are quickly trapped by the nitroxide radicals and reform the alkoxyamines. Parent class: functional group modification (RXNO:0000011)
Baeyer pyridine synthesis (RXNO:0000664) Def.: The conversion of pyran or pyrone (pyranone) derivatives to the corresponding pyridine derivative. Parent class: functional group modification (RXNO:0000011)
Corey-Kim oxidation (RXNO:0000665) Def.: Oxidation of primary and secondary alcohols via their alkoxysulfonium salts. Upon the addition of base, the salt rearranges intramolecularly to aldehydes and ketones, respectively. Parent class: functional group oxidation (RXNO:0000012)
Corey-Suggs oxidation (RXNO:0000666) Def.: Oxidation of primary and secondary alcohols to aldehydes and ketones, respectively, through the use of pyridinium chlorochromate (PCC). Parent class: functional group oxidation (RXNO:0000012)
Corey-Schmidt oxidation (RXNO:0000667) Def.: Oxidation of primary and secondary alcohols to aldehydes and ketones, respectively, through the use of pyridinium dichromate (PDC). Parent class: functional group oxidation (RXNO:0000012)
Albright-Goldman oxidation (RXNO:0000668) Def.: A particularly mild oxidation method in which, for example, dimethyl sulfoxide and acetic anhydride can be used as oxidizing agents to selectively produce aldehydes from primary alcohols without further oxidation to carboxylic acids. Analogously, secondary alcohols can be oxidized to form ketones. Parent class: functional group oxidation (RXNO:0000012)
Rubottom oxidation (RXNO:0000669) Def.: The Rubottom oxidation is a useful, high-yielding chemical reaction between silyl enol ethers and peroxy acids to give the corresponding α-hydroxy carbonyl product. Parent class: functional group oxidation (RXNO:0000012)
IBX oxidation (RXNO:00006673) Def.: Oxidation of alcohols to the corresponding carbonyl product using 2-iodoxybenzoic acid (IBX) as oxidizing agent. Parent class: functional group oxidation (RXNO:0000012)