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rsv-lineages / lineage-designation-B

RSV-B lineage definitions and proposals
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B.D.E.1.1 Proposal #1

Open doloacu opened 2 weeks ago

doloacu commented 2 weeks ago

Hello! Below, I have listed the GISAID Accession IDs of sequences that could potentially belong to the B.D.E.1.1 clade: EPI_ISL_19497475, EPI_ISL_19497497, EPI_ISL_19497476, EPI_ISL_19497498, EPI_ISL_19497473, EPI_ISL_19497495, EPI_ISL_19497474, EPI_ISL_19497496, EPI_ISL_19497471, EPI_ISL_19497493, EPI_ISL_19497472, EPI_ISL_19497494, EPI_ISL_19497491, EPI_ISL_19497470, EPI_ISL_19497492, EPI_ISL_19497479, EPI_ISL_19497477, EPI_ISL_19497499, EPI_ISL_19497478, EPI_ISL_19497490, EPI_ISL_19497464, EPI_ISL_19497486, EPI_ISL_19497465, EPI_ISL_19497487, EPI_ISL_19497462, EPI_ISL_19497484, EPI_ISL_19497463, EPI_ISL_19497485, EPI_ISL_19497482, EPI_ISL_19497483, EPI_ISL_19497480, EPI_ISL_19497481, EPI_ISL_19497505, EPI_ISL_19497506, EPI_ISL_19497503, EPI_ISL_19497504, EPI_ISL_19497468, EPI_ISL_19497501, EPI_ISL_19497469, EPI_ISL_19497502, EPI_ISL_19497466, EPI_ISL_19497488, EPI_ISL_19497467, EPI_ISL_19497489, EPI_ISL_19497500 All of them are from Argentina and belong to a monophyletic clade with good support in a phylogenetic tree alongside the reference sequences from github. The most important non-synonymous mutations are: NS1:K74E P:D225N SH:I49M G:L250P F:N190S F:N211S L:N590S L:K1759R

I am attaching the fasta file. RSV-B-20241021-GISAID.txt I look forward to your response. If there is anything I can improve, I hope you will let me know. I have tried to use the Autolin program, but I couldn't learn how to use it. Thank you in advance. Dolores Acuña

doloacu commented 8 hours ago

@rneher I hope this message finds you well. Let me know if you need any additional information to make the analysis possible. I would like to know if my hypothesis is correct. Kind regards