wtdbg2对杂合度以及重复序列敏感度的问题

ruanjue / wtdbg2

Redbean: A fuzzy Bruijn graph approach to long noisy reads assembly

GNU General Public License v3.0

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Closed Neo-xbx-00 closed 2 years ago

Neo-xbx-00 commented 2 years ago

老师您好，现有一基因组，杂合率估计为0.88%，重复序列比例为50.26%，请问应用wydbg2的算法是否合适，因为据听wtdbg2可能对较高重复度的基因组不太适用。谢谢老师

ruanjue commented 2 years ago

你试试吧，应该没问题