s-andrews / nexons

A pipeline for quantitating transcript level abundances from nanopore sequence data
GNU General Public License v3.0
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Nexons fails to identify short exons #12

Open ozgegizlenci opened 1 year ago

ozgegizlenci commented 1 year ago

Pipeline fails to identify the short exons, particularly at the ends. The first exon of the of ENSMUST00000131374.8 is very short and Nexons misaligns this exon together with second exon.

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We thought to have an alternative approach; add annotated short exons to the variants post-processing to see if it maps better in splice variant when we add short exons to variants (needs further discussion).