Questions about the LR-TF database

saeyslab / nichenetr

NicheNet: predict active ligand-target links between interacting cells

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Questions about the LR-TF database #207

Closed qijt123 closed 11 months ago

qijt123 commented 12 months ago

Thank you so much for developing the tool!

I would like to know if in the LR-TF database you collected, are all LR's effects on TF activated? Is it possible that LR's effect on TF is inhibitory?

Looking forward to your reply!

csangara commented 11 months ago

Hi!

Yes, it is possible that the effect is inhibitory (see #150), but it is not possible to screen for this specifically.