saezlab / liana

LIANA: a LIgand-receptor ANalysis frAmework
https://saezlab.github.io/liana/
GNU General Public License v3.0
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A liana consensus resource for commercial using #79

Closed menglinzheng0504 closed 1 year ago

menglinzheng0504 commented 1 year ago

Hello!

thank you for the development of Liana package. Is there a parameter of LIANA to generate the consensus only including commercial-use databases? Thanks.

Best,

dbdimitrov commented 1 year ago

Hi @menglinzheng0504,

From the figure that you shared, I believe Cellinker is the only potentially problematic resource in LIANA's consensus resource.

Perhaps, using the OmnipathR::curated_ligand_receptor_interactions function to only include the comercial-use databases is the easiest and safest way to get a resource, similar to the consensus resource in LIANA.

Hope this helps.

Daniel

@deeenes any input on this would be appreciated :)

dbdimitrov commented 1 year ago

@menglinzheng0504

Would you mind sharing your commecrial-use figure that you sent to me via email here? Could help @deeenes with potentially providing better advice in your case and others :)

menglinzheng0504 commented 1 year ago

Hi @dbdimitrov

Thank you for your reply. Here is the summary of the resources based on licenses

Screenshot 2023-01-04 103408