search

saigegit / SAIGE

Development for SAIGE and SAIGE-GENE(+)
GNU General Public License v3.0
64 stars 27 forks source link

Back calculated SE #77

Closed tom-a-bond closed 1 year ago

tom-a-bond commented 1 year ago

Hi,

We would like to use the SE back-calculated from the SPA test p-values and BETA estimated using the Firth approx, as detailed here: https://github.com/saigegit/SAIGE/issues/46

Would you mind clarifying how this is obtained please- i.e. is the SE column automatically calculated in this way when firth regression is turned on, or does the back-calculation have to be requested explicitly?

Many thanks in advance, Tom

weizhou0 commented 1 year ago

Hi Tom,

I'm so sorry for my late reply! The SE column automatically calculated in this way when firth regression is turned on.

Thanks, Wei

tom-a-bond commented 1 year ago

Brilliant, many thanks for confirming this!