This is the official development repository for BCFtools. See installation instructions and other documentation here http://samtools.github.io/bcftools/howtos/install.html
wget -N ftp://ftp.ncbi.nlm.nih.gov/pub/clinvar/vcf_GRCh38/archive_2.0/2023/clinvar_20230819.vcf.gz
echo $(seq 1 22) X Y | awk -v RS=' ' '{print $1"\tchr"$1} END {print "MT\tchrM"}' > hg38_rename.txt
bcftools annotate --rename-chrs hg38_rename.txt --write-index --threads 1 -Oz -o clinvar_20230819.hg38.vcf.gz clinvar_20230819.vcf.gz
bcftools view -H clinvar_20230819.hg38.vcf.gz chrY | head
The following error is shown at this point:
[E::get_intv] Failed to parse TBX_VCF, was wrong -p [type] used?
The offending line was: "1627532;CLNDISDB=MedGen:CN517202;CLNDN=not_provided;CLNHGVS=NC_000001.11:g.931107C>T;CLNREVSTAT=criteria_provided,_single_submitter;CLNSIG=Likely_benign;CLNVC=single_nucleotide_variant;CLNVCSO=SO:0001483;GENEINFO=SAMD11:148398;MC=SO:0001627|intron_variant;ORIGIN=1"
Error: BCF read error
Recreate another one without --threads 1 and there's no error:
Versions:
Steps to reproduce:
The following error is shown at this point:
Recreate another one without
--threads 1
and there's no error:If the index file is recreated by
bcftools index
, there's no error too:So there should be something wrong with the index file when it is produced by
--write-index
with--threads
(>0).