samtools / htslib

C library for high-throughput sequencing data formats
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Temporary workaround when excessive memory is required by FORMAT fields #1689

Closed pd3 closed 7 months ago

pd3 commented 7 months ago

The BCF limit of ~2GB per VCF row causes the parser to return an error. In this temporary solution we drop the excessive fields, typically these will be PL and other Number=G tags. in future work the library would automatically convert such tags into their localized alternatives (LPL).