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sars-cov-2-variants / lineage-proposals

Repository to propose and discuss lineages
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JN.1.1.7+S:R346T mini saltation branch with S:L455S->A, ORF7a:T28I (3 seqs in Singapore and Malaysia) #1500

Closed HynnSpylor closed 5 months ago

HynnSpylor commented 5 months ago

Defining mutations: JN.1.1.7>G22599C (S:R346T)>C5407A, C9442T, T22925G (S:L455S->A), C27476T (ORF7a:T28I)

GISAID query: C5407A, T22925G, C27476T Earliest seq: 2024-03-18 (Malaysia, EPI_ISL_19025958) Most recent seq: 2024-03-25(Singapore, EPI_ISL_19033217) Countries detected: Singapore (2), Malaysia (1)

Usher Tree: (Notice that the S:K484E rev is common artefact in Singapore) 联想截图_20240408111438

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_16ce3_3578d0.json

It is a small saltation branch from JN.1.1.7+S:R346T sublineage. As S:L455S achieves great success recently, there is still few S:L455F (for XBB FLip) and S:L455A (for some JN.1 seq S:L455S->A). We can monitor the new branch for a time.

Genomes: EPI_ISL_19025958, EPI_ISL_19033217, EPI_ISL_19033219

HynnSpylor commented 5 months ago

Oh sorry I submit the issue twice!