KP.2.3 (S:∆S31) + S:V382L, ORF1a:I3090V (142 seq, 16 countries , Aug 24)

[ryhisner]

Description Sub-lineage of: KP.2.3 (S:∆S31, H146Q, R346T, F456L, V1104L) Earliest sequence: 2024-5-14, USA, Utah — EPI_ISL_19175796 Most recent sequence: 2024-6-2, Singapore traveler to USA—EPI_ISL_19195862; New York City, USA—EPI_ISL_19189066 Continents circulating: Europe (3), Asia (3), North America (2) Countries circulating: Iceland (5), Ireland (2), Singapore (2), USA (2), India (1) Number of Sequences: 12 GISAID Nucleotide Query: G22706T, A9533G CovSpectrum Query: Nextcladepangolineage:KP.2* & G22706T & [1-of: A9533G, C29095T] Substitutions on top of KP.2.3: Spike: V382L ORF1a: I3090V Nucleotide: A9533G, G22706T, C29095T

USHER Tree https://nextstrain.org/fetch/genome-euro.ucsc.edu/trash/ct/subtreeAuspice1_genome_euro_31972a_c78810.json?label=id:node_2377461

Evidence Mainly of interest due to recency of collection, wide geographic spread, and the fact that one sequence is from a traveler from India.

Genomes

Genomes

EPI_ISL_19159306, EPI_ISL_19159313-19159314, EPI_ISL_19159318, EPI_ISL_19162365, EPI_ISL_19162491, EPI_ISL_19175796, EPI_ISL_19189066, EPI_ISL_19195199, EPI_ISL_19195626, EPI_ISL_19195862

[FedeGueli]

+3 GBW samples i think

[FedeGueli]

19 please propose it

[FedeGueli]

26 now with around 6% of prevalence in Iceland

[NkRMnZr]

This jumped to 41 probably due to a cluster from England

[FedeGueli]

BIG JUMP TO 41 FROM ENGLAND propose it @ryhisner

[FedeGueli]

50 now from 9 countries. it seems spreading in Uk Iceland Portorico and has been sampled from travelers coming from India and Singapore and in Hong Kong

[FedeGueli]

propose it

[FedeGueli]

101 , 15 countries, @ryhisner please propose it.

[FedeGueli]

119 now , today six samples uploaded from Canada with S:R214L , likely just a cluster.

[FedeGueli]

126 @ryhisner please propose it

[FedeGueli]

132

[FedeGueli]

142 Sweden

[FedeGueli]

cc @ryhisner i would propose this one