sars-cov-2-variants / lineage-proposals

Repository to propose and discuss lineages
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XDV.1.1 ( T4579A , S:S60P) with further S:H146Y, S:N185D (29 Taiwan Hubei Shanxi Hong Kong) #1820

Open FedeGueli opened 3 months ago

FedeGueli commented 3 months ago

Credits : spotted and tracked first by @memorablea in https://github.com/Memorablea/COVID-19-/issues/102#issuecomment-2208210157

T4579A was the defining of FL.2 , now popped up and seems expanding recently on XDV.1 backbone and seems successful if compared with XDV.1 4579T.

Screenshot 2024-08-03 alle 18 01 29

it further gained a S:S60P sublineage convergently with JN.1 descendants.

Defining XDV.1 > T4579A > T9208G > S:S60P (T21740C) > Orf1a:R226K (G942A)> S:H146Y (C21998T) > S:N185D (A22115G) Query for T4579A: T4579A, C1170T,C6501A,T22930A Samples: 49, first collected on 2024-04-22 in Sichuan Countries: 13 Query for S:S60P: T4579A,T9208G ,T21740 Samples: 17, first collected on 2024-04-27 in Yunnan Countries: 6 Query for 60P + H146Y + N185D: T4579A, G942A, A22115G Samples:7 Country: Hubei

Tree:

Screenshot 2024-08-03 alle 18 11 03

https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_383e7_e50380.json?f_userOrOld=uploaded%20sample

FedeGueli commented 3 months ago

Big upload from three different regions of China 66/31

FedeGueli commented 2 months ago

+3 with 60P Gansu

This is really interesting cc @corneliusroemer

xz-keg commented 2 months ago

Designated XDV.1.1 for the S60P branch VIA https://github.com/cov-lineages/pango-designation/commit/43d7733254e29c91714acb4ed0ea2003b2873551

Memorablea commented 2 months ago

should add "partially designated"

FedeGueli commented 2 months ago

i will close this for now.

FedeGueli commented 2 months ago

XDV.1.1 is one of the fastest lineage circulating with a small disadvantage vs KP.3.1.1 , now the branch with 146Y and 185D reached 20. i m reopening it.

Another mini branch of XDV.1.1 has now acquired S:D420N query: G22820A , G942A,C1387T

xz-keg commented 1 month ago

The S:H146Y,N185D branch seems to be spread all over Hubei in Xiaogan, Xiantao,Wuhan, Huangshi, Enshi, Jingzhou, Yichang, Qianjiang and Ezhou. It also spreads to Shanxi.

It shall not be a cluster, but just underrepresented due to the lack of survellience in other Chinese provinces.

FedeGueli commented 1 month ago

+1 Hubei

FedeGueli commented 1 month ago

+1 HK

FedeGueli commented 1 week ago

no chance to compete closing this

xz-keg commented 5 days ago

+1 Taiwan

FedeGueli commented 5 days ago

+1 Taiwan

super recent one, reopening for a while