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sars-cov-2-variants / lineage-proposals

Repository to propose and discuss lineages
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Small KP.3.1.1 branch with S:T572I and S:A435S and further S:A348S (2, 2 places) #2116

Closed FedeGueli closed 3 days ago

FedeGueli commented 2 weeks ago

Not sure how it will go but rapid accumulation of Spike mutations makes it worth to be highlighted.

KP.3.1.1 >> C1093T > T15750C > C26801T > Orf1b:P1645S(C18400T) > N:A119T (G28628A) > C23896T > S:T572I (C23277T) > S:A435S (G22865T) > S:A348S (G22604T) Query: G28628A, C23896T ,G22865T Samples: 2 Places : Nevada, Dominican Republic (GBW) Tree:

Screenshot 2024-10-02 alle 12 13 22

https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice6_genome_test_112d5_d120d0.json?c=gt-S_435&gmax=25384&gmin=21563&label=id:node_7213317

Interesting ( but it could be a case) that accumulation of spike mutations in this branch that evolved quietly with silent nuc mutations started after the NSP14_P121S mutation , NSP14 is the proofreading exoribonuclease of Sars Cov 2

FedeGueli commented 3 days ago

Closing