sars-cov-2-variants / lineage-proposals

Repository to propose and discuss lineages
43 stars 2 forks source link

KP.3.1.1 + S:I203V (26, 5 places US, Canada) #2129

Open FedeGueli opened 1 week ago

FedeGueli commented 1 week ago

Likely just clusters but very recent. S:I203V appears to be a very rare mutations even if it is predicted by Dadonaite and Bloom to boost binding on XBB backbone

Screenshot 2024-10-08 alle 01 04 11

Nearby mutations in that area as S:Y200C has shown to be effective in XBB.1.22.1/FY* or to a much lesser extent S:I197V

Defining mutations:Kp.3.1.1 > > A19722G > C10681T > C1973T, S:I203V (A22169G) Query: C10681T,A22169G ,C1973T Samples: 7 Places: US -2 States, Canada - 2Provinces Tree:

Screenshot 2024-10-08 alle 01 09 36

https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_5527e_465a30.json?c=userOrOld&label=id:node_7202203

FedeGueli commented 4 days ago

11 maybe clusters?

FedeGueli commented 15 hours ago

Jumped to 26 due a cluster in British Columbia