search

sars-cov-2-variants / lineage-proposals

Repository to propose and discuss lineages
43 stars 2 forks source link

XEC + ORF1b:P1664S, ORF1a:M1771V (101 mainly in Ontario) #2200

Open Fearuncle opened 2 days ago

Fearuncle commented 2 days ago

XEC>> C19983T > T1993C, Orf1a:M1771V (A5576G = PLPro_M208V) , Orf1b:P1664S (C18457T) [Edited]

tree: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1787b_845120.json?f_userOrOld=uploaded%20sample image

First Seq: 2024-09-17 Most Recent: 2024-10-21

Gisaid: T1993C, A5576G,T3565C (Edited to exclude an old sample from Serbia unrelated)

EPI_ISL_19514813 EPI_ISL_19494949 EPI_ISL_19494945 EPI_ISL_19515243 EPI_ISL_19515332 EPI_ISL_19482968 EPI_ISL_19495020 EPI_ISL_19482877 EPI_ISL_19514735 EPI_ISL_19515158 EPI_ISL_19514841 EPI_ISL_19514942 EPI_ISL_19515056 EPI_ISL_19494658 EPI_ISL_19457640 EPI_ISL_19495080 EPI_ISL_19483375 EPI_ISL_19494933 EPI_ISL_19494947 EPI_ISL_19470726 EPI_ISL_19514675 EPI_ISL_19494538 EPI_ISL_19494951 EPI_ISL_19457823 EPI_ISL_19494536 EPI_ISL_19514536 EPI_ISL_19483633 EPI_ISL_19483397 EPI_ISL_19515285 EPI_ISL_19457541 EPI_ISL_19495008 EPI_ISL_19457291 EPI_ISL_19494652 EPI_ISL_19514845 EPI_ISL_19515157 EPI_ISL_19514937 EPI_ISL_19515001

FedeGueli commented 2 days ago

This has a PLPro mutation PLPRo_M208V

cvejris commented 1 day ago

14 (of total 101) seqs have additional N:A208S (G28895T). Very close to N:A211V, tracked in Branch 33 in https://github.com/sars-cov-2-variants/lineage-proposals/issues/2088. Wonder if this is peculiar for Canada (which has been experiencing long and well-monitored XEC infection) or if nucleocapsid mutations will start to pop up elsewhere.

FedeGueli commented 1 day ago

14 (of total 101) seqs have additional N:A208S (G28895T). Very close to N:A211V, tracked in #2200. Wonder if this is peculiar for Canada (which has been experiencing long and well-monitored XEC infection) or if nucleocapsid mutations will start to pop up elsewhere.

2200 is this one, which one did u mean to tag?

cvejris commented 1 day ago

14 (of total 101) seqs have additional N:A208S (G28895T). Very close to N:A211V, tracked in #2200. Wonder if this is peculiar for Canada (which has been experiencing long and well-monitored XEC infection) or if nucleocapsid mutations will start to pop up elsewhere.

2200 is this one, which one did u mean to tag?

Edited, thanx for notifying me and sorry for the wrong link

FedeGueli commented 1 day ago

14 (of total 101) seqs have additional N:A208S (G28895T). Very close to N:A211V, tracked in #2200. Wonder if this is peculiar for Canada (which has been experiencing long and well-monitored XEC infection) or if nucleocapsid mutations will start to pop up elsewhere.

2200 is this one, which one did u mean to tag?

Edited, thanx for notifying me and sorry for the wrong link

No worries, thanks