Stepwise evolution led to a new XBB.2.3.7 sublineage with S:Q314E, ORF9b:L14F & NG18C circulating in NZL & Australia (20)

[FedeGueli]

Tree: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_17457_659430.json?c=gt-S_314,1263&label=id:node_7038264

Defining mutations:

XBB.2.3.7>>> S:P1263R (C25350G) > Orf8:Y42C (A28018G) > T18669C >Orf1a:M3862I (NSP7_V3I = G11851T )> S:Q314E (C22502G) , N:G18C (G28325T) = Orf9b:L14F , Orf10:R24C (C29627T)

Gisaid query: C22502G,G28325T,C29627T,G11851T

Samples 19 Australia/VIC-VIDRL-00009723/2023|EPI_ISL_17823068|2023-05-01 Australia/VIC83874/2023|EPI_ISL_17657168|2023-05-05 Australia/VIC84709/2023|EPI_ISL_17802667|2023-05-22 Australia/VIC84711/2023|EPI_ISL_17802669|2023-05-22 Australia/VIC84710/2023|EPI_ISL_17802668|2023-05-22 Australia/VIC84227/2023|EPI_ISL_17802227|2023-05-12 Australia/VIC84613/2023|EPI_ISL_17802588|2023-05-16 Australia/VIC84202/2023|EPI_ISL_17802204|2023-05-11 Australia/VIC84228/2023|EPI_ISL_17802228|2023-05-15 Australia/VIC84944/2023|EPI_ISL_17802888|2023-05-25 Australia/VIC85051/2023|EPI_ISL_17802991|2023-05-29 Australia/VIC85014/2023|EPI_ISL_17802955|2023-05-30 hCoV-19/Australia/VIC85343/2023|EPI_ISL_17803263|2023-06-02 Australia/VIC85343/2023|EPI_ISL_17803263|2023-06-02 hCoV-19/New_Zealand/ESR-ZA3103/2023|EPI_ISL_17962198|2023-06-06 hCoV-19/New_Zealand/ESR-XA3478/2023|EPI_ISL_17962132|2023-06-12 hCoV-19/New_Zealand/ESR-YA3550/2023|EPI_ISL_17961956|2023-06-16 hCoV-19/New_Zealand/ESR-YA3542/2023|EPI_ISL_17961952|2023-06-18 hCoV-19/New_Zealand/ESR-YA3671/2023|EPI_ISL_17961932|2023-06-19 hCoV-19/New_Zealand/ESR-YA3670/2023|EPI_ISL_17961931|2023-06-19 hCoV-19/New_Zealand/ESR-YA3663/2023|EPI_ISL_17961929|2023-06-19

[FedeGueli]

still 19 seems slow. lets wait the next NZL batch.