XBB.2.3.3 with S:T478R (51 Thailand, China, South Korea, Australia )

[FedeGueli]

XBB.2.3.3 recently acquired S:T478R as several siblings of it.

Tree: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1d276_62a560.json?c=userOrOld&label=id:node_7069562

Defining mutations: XBB.2.3.3 >> C19884T, C13138T> A11794G, S:T478R (A22995G)

Gisaid query: C19884T, C13138T,A11794G

Samples: 16 First: hCoV-19/Thailand/TROPMED-0179/2023 | Original | EPI_ISL_17952206 | 2023-04-20 Last: hCoV-19/Thailand/NIC_UDN_6946/2023 | Original | EPI_ISL_17980180 | 2023-07-04

IDs: EPI_ISL_17622144, EPI_ISL_17624077, EPI_ISL_17683098, EPI_ISL_17692219, EPI_ISL_17696820, EPI_ISL_17816161, EPI_ISL_17835426, EPI_ISL_17952206, EPI_ISL_17956877, EPI_ISL_17980180, EPI_ISL_17984544, EPI_ISL_17984546, EPI_ISL_17987920, EPI_ISL_17994632, EPI_ISL_17994656, EPI_ISL_17994683

Countries:

[FedeGueli]

jumpt to 20 seqs. around 5% of recent samples from Thailand

[FedeGueli]

cc @corneliusroemer

[FedeGueli]

• 9 : S.Korea, Thailand , Haute Garonne, Alberta, Dublin , Texas

[FedeGueli]

Spain , NYC, Wales and two gbw samples (likely one patient from Uk) this is to keep monitored.

Growth advantage : https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?aaMutations=Orf1b%3AD54N&nucMutations1=C19884T%2CC13138T%2CA11794G&analysisMode=CompareToBaseline&

@ryhisner @hynnspylor @corneliusroemer @aviczhl2 worth proposing it?

[xz-keg]

Of course.

Emerging lineage with high growth advantage, global spread and known beneficial mutation. I can't think of a reason not to propose this.

[FedeGueli]

proposed

[FedeGueli]

Designated GJ.5 and GJ.5.1 via https://github.com/cov-lineages/pango-designation/commit/897f423b48cc98132cf611f0e4b0e95cc960c32a and https://github.com/cov-lineages/pango-designation/commit/712224206fb032c45ba4e1b4f6ee33c80662a396 see issue on Pango for 255F