XBB.1.9.2 with S:V1122L (81 seqs, mainly in Spain, 8 countries)

[NkRMnZr]

Defining Mutations: XBB.1.9.2 > C21622T > A14673G > T9508C > C673T, G24926T(S:V1122L) Query: C673T, T9508C, G24926T, -T3576C Earliest seq: 2023-03-22 (EPI_ISL_17482696, Sevilla, Spain) Latest seq: 2023-07-06 (EPI_ISL_18011161, California, USA) Sampled Countries: Spain (50, Mainland/49, Canary Islands/1 ), USA (15), Canada (3), Austria (2), UK (2, England, Scotland), Belgium (1), France (1), Iceland (1)

Genomes:

EPI_ISL_17482696, EPI_ISL_17482745, EPI_ISL_17482800, EPI_ISL_17541202, EPI_ISL_17541229, EPI_ISL_17541240, EPI_ISL_17592159, EPI_ISL_17638016, EPI_ISL_17669025, EPI_ISL_17669099, EPI_ISL_17669122, EPI_ISL_17669143, EPI_ISL_17669244, EPI_ISL_17669728, EPI_ISL_17678986-17678987, EPI_ISL_17679198, EPI_ISL_17679245, EPI_ISL_17679377-17679378, EPI_ISL_17679443, EPI_ISL_17679445, EPI_ISL_17679519, EPI_ISL_17679529, EPI_ISL_17679544, EPI_ISL_17679546, EPI_ISL_17679688, EPI_ISL_17679691, EPI_ISL_17719463, EPI_ISL_17731340, EPI_ISL_17731355, EPI_ISL_17731371, EPI_ISL_17731418-17731419, EPI_ISL_17731424-17731425, EPI_ISL_17731429, EPI_ISL_17731431, EPI_ISL_17732319, EPI_ISL_17735006, EPI_ISL_17743015, EPI_ISL_17781607, EPI_ISL_17782295, EPI_ISL_17795927, EPI_ISL_17795966, EPI_ISL_17804456, EPI_ISL_17809741, EPI_ISL_17812691, EPI_ISL_17814775, EPI_ISL_17817615, EPI_ISL_17817706, EPI_ISL_17817892, EPI_ISL_17830861, EPI_ISL_17849282, EPI_ISL_17850570, EPI_ISL_17854250, EPI_ISL_17948633, EPI_ISL_17948642, EPI_ISL_17948671, EPI_ISL_17949014, EPI_ISL_17949027, EPI_ISL_17949089, EPI_ISL_17949195, EPI_ISL_17971523, EPI_ISL_17972054, EPI_ISL_17976686, EPI_ISL_17978961, EPI_ISL_17979120, EPI_ISL_17979266, EPI_ISL_17989504, EPI_ISL_17995465, EPI_ISL_18001506, EPI_ISL_18011160-18011161

UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_25ae9_d37930.json?f_userOrOld=uploaded%20sample&label=id:node_6704508

Trivia:

• hCoV-19/Spain/CT-LabRefCat-4864840/2023|EPI_ISL_17806705|2023-05-24 seems to be a recombination with XBB.1.5, placed under a weird flip-flop sub-branch of it, the query is using -T3576C to filter it out.

[FedeGueli]

S:V1122L is predicted to be advantageous.

[NkRMnZr]

Tracking updates:

07-28: 4 seqs from Canada and USA: EPI_ISL_18012810, EPI_ISL_18030073, EPI_ISL_18037687, EPI_ISL_18043050 08-01: 3 seqs from USA

[NkRMnZr]

08-01: 3 seqs from USA: EPI_ISL_18053907, EPI_ISL_18054668, EPI_ISL_18054681

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_408b6_8e4b40.json?f_userOrOld=uploaded%20sample

[FedeGueli]

Please propose it

[NkRMnZr]

Transferred to cov-lineages/pango-designation#2158