sars-cov-2-variants / lineage-proposals

Repository to propose and discuss lineages
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EG.5.1.6 sublineage with S:N211I (73 seqs in 7 countries, ) #589

Closed HynnSpylor closed 1 year ago

HynnSpylor commented 1 year ago

Defining mutations: EG.5.1.6>C1684T, A22194T (S:N211I) GISAID query: C1684T, C5835T, A22194T, C22033A Earliest seq: 2023-07-13 (Ireland- EPI_ISL_18033615) Most recent seq: 2023-08-02 (Ireland- EPI_ISL_18092164) Countries detected: Ireland (11), US (1), UK (1, detected from US International Airport), Spain (1), China (1)

Usher Tree:

屏幕截图 2023-08-11 114918

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_ee4d_5adb70.json?c=gt-S_211

EG.5.1.6 (with S:F157L) is one of rapidly increasing lineages. Now the branch with S:N211I has shown international transmission, and a rapid view may be needed.

I'll propose it in main page when it reaches 20.

Genomes: EPI_ISL_18033615, EPI_ISL_18056978, EPI_ISL_18056987, EPI_ISL_18060774, EPI_ISL_18072782, EPI_ISL_18092133, EPI_ISL_18092139-18092140, EPI_ISL_18092143, EPI_ISL_18092145-18092146, EPI_ISL_18092153, EPI_ISL_18092162, EPI_ISL_18092164-18092165,

FedeGueli commented 1 year ago

Great catch Hynn, EG.5.1.6 seems to be a great backbone . Interestingly one branch of it got orf1a:Q556R similar to the K defining of BA.5.3.1/BE.1/BQ family

HynnSpylor commented 1 year ago

2 more seqs from Spain

HynnSpylor commented 1 year ago

3 more seqs from Ireland, total is 20 I'll propose it in main page

FedeGueli commented 1 year ago

20 please go!

FedeGueli commented 1 year ago

It slowed a lot. lets keep it here for now.

FedeGueli commented 1 year ago

Grew to 73 and 2 more countries but too slow to compete: https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?nextcladePangoLineage=HK.3*&nucMutations1=C1684T%2CC5835T%2CA22194T%2CC22033A&analysisMode=CompareToBaseline&