Closed rcavalcante closed 9 years ago
Yes, adding a minimum limit like 0.01 is fine. I can’t imagine anyone being interested in a difference so small.
From: Raymond Cavalcante [mailto:notifications@github.com] Sent: Thursday, May 28, 2015 1:01 PM To: sartorlab/methylSig Subject: [methylSig] Scientific notation output of methylation differences (#3)
Writing a methylSigDiff object to a file can result in scientific notation for methylation differences when the differences are very small. For example,
chr14 38340169 38340169 -2.37233043431928e-05 chr14 50108792 50108792 -3.51720594760074e-05 chr15 99978267 99978267 9.84861037167661e-07
gives the following error when turning a bedGraph into a bigWig (using bedGraphToBigWig):
invalid unsigned integer: "1.35e+08"
Perhaps any difference below 0.01 (or some other threshold) should be set to 0?
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Fixed with commit e153b3f6cc02761ff6f2515876e880aca8225058 in devel.
Writing a methylSigDiff object to a file can result in scientific notation for methylation differences when the differences are very small. For example,
chr14 38340169 38340169 -2.37233043431928e-05
chr14 50108792 50108792 -3.51720594760074e-05
chr15 99978267 99978267 9.84861037167661e-07
gives the following error when turning a bedGraph into a bigWig (using
bedGraphToBigWig
):invalid unsigned integer: "1.35e+08"
Perhaps any difference below 0.01 (or some other threshold) should be set to 0?