Recently, I tried to use the bone marrow dataset ("bmcite") as reference to annotate single-cell data in my study. I noticed that l2 level annotations were available in the metadata slot. Although most of the these annotations were easy to understand, types such as 'CD8 Effector_1', 'CD8 Effector_2', 'CD8 Memory_1', 'CD8 Memory_2' were difficult to understand. I guess there are some markers that discriminate them?
Then I tried to find the answers in the paper that published this dataset. Unfortunately, I couldn't find any details about these cell types. Could anyone tell me the full name of these L2 annotations?
You can find heatmaps of genes that define these annotations in Supplementary Figure 2G (link). Hopefully that makes the distinctions a bit more clear.
Dear Seurat team members,
Thank you for generating these valuable datasets!
Recently, I tried to use the bone marrow dataset ("bmcite") as reference to annotate single-cell data in my study. I noticed that l2 level annotations were available in the metadata slot. Although most of the these annotations were easy to understand, types such as 'CD8 Effector_1', 'CD8 Effector_2', 'CD8 Memory_1', 'CD8 Memory_2' were difficult to understand. I guess there are some markers that discriminate them?
Then I tried to find the answers in the paper that published this dataset. Unfortunately, I couldn't find any details about these cell types. Could anyone tell me the full name of these L2 annotations?
Thanks,