This PR was automatically created by Snyk using the credentials of a real user.
Snyk has created this PR to fix one or more vulnerable packages in the `pip` dependencies of this project.
#### Changes included in this PR
- Changes to the following files to upgrade the vulnerable dependencies to a fixed version:
- requirements.txt
⚠️ Warning
```
marshmallow-sqlalchemy 0.29.0 has requirement marshmallow>=3.0.0, but you have marshmallow 2.21.0.
Flask 1.1.4 has requirement itsdangerous<2.0,>=0.24, but you have itsdangerous 2.1.2.
Flask-JWT-Extended 3.25.1 has requirement PyJWT<2.0,>=1.6.4, but you have PyJWT 2.7.0.
Flask-AppBuilder 2.3.4 has requirement email-validator<2,>=1.0.5, but you have email-validator 2.0.0.post2.
cattrs 1.10.0 has requirement attrs>=20, but you have attrs 19.3.0.
botocore 1.29.163 has requirement urllib3<1.27,>=1.25.4, but you have urllib3 2.0.3.
```
#### Vulnerabilities that will be fixed
##### By pinning:
Severity | Priority Score (*) | Issue | Upgrade | Breaking Change | Exploit Maturity
:-------------------------:|-------------------------|:-------------------------|:-------------------------|:-------------------------|:-------------------------
 | **435/1000** **Why?** Has a fix available, CVSS 4.2 | Open Redirect [SNYK-PYTHON-AIOHTTP-1079232](https://snyk.io/vuln/SNYK-PYTHON-AIOHTTP-1079232) | `aiohttp:` `3.6.2 -> 3.8.0` | No | No Known Exploit
 | **686/1000** **Why?** Proof of Concept exploit, Has a fix available, CVSS 7.3 | HTTP Header Injection [SNYK-PYTHON-AIOHTTP-1584144](https://snyk.io/vuln/SNYK-PYTHON-AIOHTTP-1584144) | `aiohttp:` `3.6.2 -> 3.8.0` | No | Proof of Concept
 | **506/1000** **Why?** Proof of Concept exploit, Has a fix available, CVSS 3.7 | NULL Pointer Dereference [SNYK-PYTHON-NUMPY-2321964](https://snyk.io/vuln/SNYK-PYTHON-NUMPY-2321964) | `numpy:` `1.21.3 -> 1.22.2` | No | Proof of Concept
 | **399/1000** **Why?** Has a fix available, CVSS 3.7 | Buffer Overflow [SNYK-PYTHON-NUMPY-2321966](https://snyk.io/vuln/SNYK-PYTHON-NUMPY-2321966) | `numpy:` `1.21.3 -> 1.22.2` | No | No Known Exploit
 | **506/1000** **Why?** Proof of Concept exploit, Has a fix available, CVSS 3.7 | Denial of Service (DoS) [SNYK-PYTHON-NUMPY-2321970](https://snyk.io/vuln/SNYK-PYTHON-NUMPY-2321970) | `numpy:` `1.21.3 -> 1.22.2` | No | Proof of Concept
 | **509/1000** **Why?** Has a fix available, CVSS 5.9 | Regular Expression Denial of Service (ReDoS) [SNYK-PYTHON-SETUPTOOLS-3180412](https://snyk.io/vuln/SNYK-PYTHON-SETUPTOOLS-3180412) | `setuptools:` `39.0.1 -> 65.5.1` | No | No Known Exploit
(*) Note that the real score may have changed since the PR was raised.
Some vulnerabilities couldn't be fully fixed and so Snyk will still find them when the project is tested again. This may be because the vulnerability existed within more than one direct dependency, but not all of the affected dependencies could be upgraded.
Check the changes in this PR to ensure they won't cause issues with your project.
------------
**Note:** *You are seeing this because you or someone else with access to this repository has authorized Snyk to open fix PRs.*
For more information:
🧐 [View latest project report](https://app.snyk.io/org/scielo/project/ec47df20-5fbd-4c54-99e3-fa03fe413cc4?utm_source=github&utm_medium=referral&page=fix-pr)
🛠 [Adjust project settings](https://app.snyk.io/org/scielo/project/ec47df20-5fbd-4c54-99e3-fa03fe413cc4?utm_source=github&utm_medium=referral&page=fix-pr/settings)
📚 [Read more about Snyk's upgrade and patch logic](https://support.snyk.io/hc/en-us/articles/360003891078-Snyk-patches-to-fix-vulnerabilities)
[//]: # (snyk:metadata:{"prId":"c457e593-140d-4557-8a22-af6a2cfc2a20","prPublicId":"c457e593-140d-4557-8a22-af6a2cfc2a20","dependencies":[{"name":"aiohttp","from":"3.6.2","to":"3.8.0"},{"name":"numpy","from":"1.21.3","to":"1.22.2"},{"name":"setuptools","from":"39.0.1","to":"65.5.1"}],"packageManager":"pip","projectPublicId":"ec47df20-5fbd-4c54-99e3-fa03fe413cc4","projectUrl":"https://app.snyk.io/org/scielo/project/ec47df20-5fbd-4c54-99e3-fa03fe413cc4?utm_source=github&utm_medium=referral&page=fix-pr","type":"auto","patch":[],"vulns":["SNYK-PYTHON-AIOHTTP-1079232","SNYK-PYTHON-AIOHTTP-1584144","SNYK-PYTHON-NUMPY-2321964","SNYK-PYTHON-NUMPY-2321966","SNYK-PYTHON-NUMPY-2321970","SNYK-PYTHON-SETUPTOOLS-3180412"],"upgrade":[],"isBreakingChange":false,"env":"prod","prType":"fix","templateVariants":["pr-warning-shown","priorityScore"],"priorityScoreList":[435,686,506,399,506,509],"remediationStrategy":"vuln"})
---
**Learn how to fix vulnerabilities with free interactive lessons:**
🦉 [Open Redirect](https://learn.snyk.io/lessons/open-redirect/python/?loc=fix-pr)
🦉 [NULL Pointer Dereference](https://learn.snyk.io/lessons/null-dereference/cpp/?loc=fix-pr)
🦉 [Denial of Service (DoS)](https://learn.snyk.io/lessons/redos/javascript/?loc=fix-pr)
This PR was automatically created by Snyk using the credentials of a real user.
Snyk has created this PR to fix one or more vulnerable packages in the `pip` dependencies of this project.
#### Changes included in this PR - Changes to the following files to upgrade the vulnerable dependencies to a fixed version: - requirements.txt⚠️ Warning
``` marshmallow-sqlalchemy 0.29.0 has requirement marshmallow>=3.0.0, but you have marshmallow 2.21.0. Flask 1.1.4 has requirement itsdangerous<2.0,>=0.24, but you have itsdangerous 2.1.2. Flask-JWT-Extended 3.25.1 has requirement PyJWT<2.0,>=1.6.4, but you have PyJWT 2.7.0. Flask-AppBuilder 2.3.4 has requirement email-validator<2,>=1.0.5, but you have email-validator 2.0.0.post2. cattrs 1.10.0 has requirement attrs>=20, but you have attrs 19.3.0. botocore 1.29.163 has requirement urllib3<1.27,>=1.25.4, but you have urllib3 2.0.3. ```**Why?** Has a fix available, CVSS 4.2 | Open Redirect
[SNYK-PYTHON-AIOHTTP-1079232](https://snyk.io/vuln/SNYK-PYTHON-AIOHTTP-1079232) | `aiohttp:`
`3.6.2 -> 3.8.0`
| No | No Known Exploit  | **686/1000**
**Why?** Proof of Concept exploit, Has a fix available, CVSS 7.3 | HTTP Header Injection
[SNYK-PYTHON-AIOHTTP-1584144](https://snyk.io/vuln/SNYK-PYTHON-AIOHTTP-1584144) | `aiohttp:`
`3.6.2 -> 3.8.0`
| No | Proof of Concept  | **506/1000**
**Why?** Proof of Concept exploit, Has a fix available, CVSS 3.7 | NULL Pointer Dereference
[SNYK-PYTHON-NUMPY-2321964](https://snyk.io/vuln/SNYK-PYTHON-NUMPY-2321964) | `numpy:`
`1.21.3 -> 1.22.2`
| No | Proof of Concept  | **399/1000**
**Why?** Has a fix available, CVSS 3.7 | Buffer Overflow
[SNYK-PYTHON-NUMPY-2321966](https://snyk.io/vuln/SNYK-PYTHON-NUMPY-2321966) | `numpy:`
`1.21.3 -> 1.22.2`
| No | No Known Exploit  | **506/1000**
**Why?** Proof of Concept exploit, Has a fix available, CVSS 3.7 | Denial of Service (DoS)
[SNYK-PYTHON-NUMPY-2321970](https://snyk.io/vuln/SNYK-PYTHON-NUMPY-2321970) | `numpy:`
`1.21.3 -> 1.22.2`
| No | Proof of Concept  | **509/1000**
**Why?** Has a fix available, CVSS 5.9 | Regular Expression Denial of Service (ReDoS)
[SNYK-PYTHON-SETUPTOOLS-3180412](https://snyk.io/vuln/SNYK-PYTHON-SETUPTOOLS-3180412) | `setuptools:`
`39.0.1 -> 65.5.1`
| No | No Known Exploit (*) Note that the real score may have changed since the PR was raised. Some vulnerabilities couldn't be fully fixed and so Snyk will still find them when the project is tested again. This may be because the vulnerability existed within more than one direct dependency, but not all of the affected dependencies could be upgraded. Check the changes in this PR to ensure they won't cause issues with your project. ------------ **Note:** *You are seeing this because you or someone else with access to this repository has authorized Snyk to open fix PRs.* For more information: