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scottzijiezhang / RADAR

The project for analyzing differential methylation of MeRIP-seq data
GNU General Public License v3.0
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Error in diffIP_parallel #14

Open huipan1973 opened 3 years ago

huipan1973 commented 3 years ago

I install the current version of RADR. I then get the following error in diffIP_parallel

error: inv(): matrix seems singular Error in PoissionGamma_multiple_beta(Y, X.all, beta, psi, mu2, gamma = 0.25, : inv(): matrix seems singular

It was fine with the older RADAR version I have installed some time ago. I am using the same data and code but get this error.

Regards Hui

kandarpRJ commented 3 years ago

@scottzijiezhang I am also getting error while running diffIP_parallel and similar to previous comment, it was working fine in previous version. For me I get warning while running diffIP_parallel

Warning message: In p.adjust(all.est[, "p_value"], method = fdrBy) : NAs introduced by coercion

and after running reportResult following error is thrown

Error in abs(stats[, "beta"]) : non-numeric argument to mathematical function

Also I noticed that for the diffIP_parallel and diffIP the number of differential sites are different in new version. Can you suggest a fix?

mitharuka commented 3 years ago

Hi @scottzijiezhang, I am also getting the same error. And this happens when I try to include covariate in diffIP_parallel. I would appreciate your suggestion to fix this.

Regards, Haruka