scverse / scirpy

A scanpy extension to analyse single-cell TCR and BCR data.
https://scirpy.scverse.org/en/latest/
BSD 3-Clause "New" or "Revised" License
219 stars 34 forks source link

antigen specificity prediction #371

Open grst opened 2 years ago

grst commented 2 years ago

Description of feature

The first reasonable methods to predict antigen specificity emerge, e.g.

These are conceptually different from querying databases through sequence distance metrics or autoencoders, as they do not simply model the sequence similarity, but explicitly model the specificity.

Would be nice to call them directly from scirpy.

@FFinotello, potentially another good student task.

grst commented 2 months ago

A new, interesting method: https://www.nature.com/articles/s43588-024-00653-0