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scverse / scirpy

A scanpy extension to analyse single-cell TCR and BCR data.
https://scirpy.scverse.org/en/latest/
BSD 3-Clause "New" or "Revised" License
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Add the Morisita-Horn index for repertoire overlap similarity scores #488

Open NicolasSompairac opened 5 months ago

NicolasSompairac commented 5 months ago

Hi there,

I've recently started using scirpy for TCR analyses. For the repertoire overlap, the scipy distances are the only available scores it seems (with Jaccard being the default one).

Do you think it would be possible to also integrate the Morisita-Horn similarity index, as it seems to be the standard measure used in most publications?

Best,

Nicolas

grst commented 5 months ago

Sure, I'd be happy to support this. Could you point me to 1-2 publications where this has been used?