Alleloscope is a method for allele-specific copy number estimation that can be applied to single cell DNA and ATAC sequencing data (separately or in combination). Allele-specific estimation allows for the more accurate delineation of copy number states and the detection of subclonal copy-neutral loss-of-heterozygosity and mirrored CNA events. On scATAC-seq data, Alleloscope allows integrative multi-omic analysis of allele-specific copy number and chromatin accessibility for the same cell.
Our bam files were aligned to human reference with the version hs1.fa. Can you provide centromere and telomere data for hs1? or the way to generate these data?
Our bam files were aligned to human reference with the version hs1.fa. Can you provide centromere and telomere data for hs1? or the way to generate these data?