Alleloscope is a method for allele-specific copy number estimation that can be applied to single cell DNA and ATAC sequencing data (separately or in combination). Allele-specific estimation allows for the more accurate delineation of copy number states and the detection of subclonal copy-neutral loss-of-heterozygosity and mirrored CNA events. On scATAC-seq data, Alleloscope allows integrative multi-omic analysis of allele-specific copy number and chromatin accessibility for the same cell.
Hello,
I've tried to run the pipeline's steps for ATACseq data and even with the "test" data I have a problem with cov_cna_plot.pdf. The code doesn't make an error and say that the plot was successfully generated and the file is not empty, but i cannot open it afterwards.
Hello, I've tried to run the pipeline's steps for ATACseq data and even with the "test" data I have a problem with cov_cna_plot.pdf. The code doesn't make an error and say that the plot was successfully generated and the file is not empty, but i cannot open it afterwards.
Do you know why this happens ?
Thank you