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segrelab / comets

Computation of Microbial Ecosystems in Time and Space
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Lexicographic optimization #49

Closed liaochen1988 closed 4 months ago

liaochen1988 commented 6 months ago

Happy new year! I am new to Comets. Does Comets enable lexicographic optimization, where different objectives can be ranked and optimized sequentially? For example, we first maximize biomass production, then minimize acetate secretion, then minimize succinate secretion, etc. Currently, it seems that Comets implements biomass production maximization followed by minimization of total flux. This is already very useful. It would be great if optimization can be more flexible for users.

dukovski commented 4 months ago

We do have the possibility to run several optimizations. We don't have it fully supported by cometspy yet though. If interested we can implement it, and you are welcome to join the development. Thanks!