Added the metadata_require_mutations which does exactly this. By default samples are ignored unless they have at least 1 mutation (doesn't matter what mutation it is - a.k.a doesn't need to be in topn genes, just anywhere in the original .data dataframe)
set metadata_require_mutations = TRUE to include these samples, but only do this if you're sure the sample has ZERO mutations. Unless your doing targeted panel sequencing, seeing 0 mutations is very unlikely
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Added the
metadata_require_mutationswhich does exactly this. By default samples are ignored unless they have at least 1 mutation (doesn't matter what mutation it is - a.k.a doesn't need to be in topn genes, just anywhere in the original .data dataframe)set
metadata_require_mutations = TRUEto include these samples, but only do this if you're sure the sample has ZERO mutations. Unless your doing targeted panel sequencing, seeing 0 mutations is very unlikely