Closed selkamand closed 3 months ago
See https://github.com/selkamand/sigshared/issues/8
It is important to allow signature fractions to sum to <1 during signature reconstruction since you commonly do NOT have models that explain 100% of the observed mutations
See https://github.com/selkamand/sigshared/issues/8
It is important to allow signature fractions to sum to <1 during signature reconstruction since you commonly do NOT have models that explain 100% of the observed mutations