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Predicting indel polymorphisms in homopolymer runs #48

Open GoogleCodeExporter opened 8 years ago

GoogleCodeExporter commented 8 years ago 
Error model needs to account for the chances of an indel at each base in the 
homopolymer run (where the error probabilities need to be applies to each base 
in the run, at least, and really should actually be larger than single base 
indel rates account for, esp. in cases of certain technologies like 454 reads). 

This is currently the major source of false-positive polymorphism predictions.

Original issue reported on code.google.com by jeffrey....@gmail.com on 24 Jul 2012 at 12:50